Prescribing antidepressant drugs is becoming common. These drugs are known to affect sexual functions. All drugs were administered by oral gavage for 35 days. After excision of caudal epididymis, it was located in 1 mL Ham's F10 medium at 37oC for 15 min and then analysis of sperm parameters was performed. To examine lipid peroxidation and total antioxidant capacity, the MDA and 1, 1-Diphenylpicryl-hydrazyl were measured, respectively.
Can antidepressants cause male infertility? | GPonline
Researchers suggest that men taking SSRIs suffer a drop in sperm counts. Emma Baines investigates. What is the story? Antidepressants such as Prozac fluoxetine could be responsible for reduced fertility in men, according to media reports. The papers reported that researchers in the US had found that SSRIs, which are taken by millions of people in the UK for the treatment of depression, could be damaging male fertility.
Effects of amitriptyline on semen of infertile men
A clinical evaluation of the effects of the antidepressive drug amitriptyline on the semen of 20 infertile men with oligoasthenozoospermia was carried out. Quantitative assessment of semen in the whole group showed significantly higher sperm counts, an increased proportion with normal sperm morphology and an increased semen volume after treatment, with a high positive correlation between sperm count before and after treatment. It would seem that amitriptyline has a beneficial effect on semen in some of these patients. Tags Type your tag names separated by a space and hit enter. Br J Urol.
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