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Ascorbic acid anal insufflation

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The fact that the medical applications are numerous exposes the ozonetherapist to medical derision because superficial observers or sarcastic sceptics consider ozonetherapy as the modern panacea. This seems so because ozone, like oxygen, is a molecule able to act simultaneously on several blood components with different functions but, as we shall discuss, ozonetherapy is not a panacea. One of the substantial differences between classical pharmacology and ozonetherapy is that this approach generates a heterogeneous number of compounds, which, in submicromolar concentrations, can trigger a variety of functional activities, hence multiple therapeutic responses rarely obtainable with a single drug. We know that chronic diseases are the result of a number of dysfunctions and the use of a reductionist approach can be disadvantageous. Indeed atherosclerotic patients often complain that during the day they must remember to take six or seven drugs such as a statin, folic acid, antioxidants, an antiaggregant agent, an anticoagulant, an ACE-inhibitor etc. This example is mentioned not for disregarding conventional medicine but to point out a reality that presents some problems with compliance and eventual outcome.
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Ascorbic acid anal insufflation

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The Clinical Application of Ozonetherapy

Since the repair and the tensile strength of wounds in soft tissues are direct functions of the proliferation of fibroblasts and the formation of collagen, it is evident that vitamin C plays an important role in the phenomenon of wound healing. Saitta 2 reported delayed healing of exposed surface wounds in guinea pigs that had been kept on a vitamin C—deficient diet for more than fifteen days. On the other hand, when a vitamin C—containing extract was applied directly to the wound, the time of healing was appreciably diminished, regardless of whether the animals were maintained on a normal or a scorbutic dietary regimen. He determined the rate. Arch Otolaryngol.
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The Clinical Application of Ozonetherapy

The potential mechanisms of action of ozone therapy are reviewed in this paper. The therapeutic efficacy of ozone therapy may be partly due the controlled and moderate oxidative stress produced by the reactions of ozone with several biological components. The line between effectiveness and toxicity of ozone may be dependent on the strength of the oxidative stress.
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